During the Master’s project (M1 or M2), the student will use some of the techniques used in the laboratory to quantitatively interrogate the structure-function relationship underlying interallelic interactions.
During this master project (M1 or M2), the student will analyze the dynamics of PRC1 dots during neuronal specification and maintenance by in vivo time-lapse imaging, and characterize the nature of these dots.
The successful completion of the project will allow you to answer how mechanical tension is generated inside human myofibers by integrating intracellular molecular forces and extracellular mechanical environment.
Project title: Investigating the mechanobiology of self-organisation in human iPSC-derived skeletal muscles Type of rotation: M1 (2 months) or M2 (6 months) Supervisors: Qiyan MAO
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