{"id":23487,"date":"2026-05-11T15:46:32","date_gmt":"2026-05-11T13:46:32","guid":{"rendered":"https:\/\/staging.wp-ibdm.nicolasg.fr\/?p=23487"},"modified":"2026-05-11T18:31:20","modified_gmt":"2026-05-11T16:31:20","slug":"keynote-seminar-stein-aerts-genome-to-function-modeling","status":"publish","type":"post","link":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/keynote-seminar-stein-aerts-genome-to-function-modeling\/","title":{"rendered":"S\u00e9minaire invit\u00e9 : Stein Aerts | 22 mai 2026"},"content":{"rendered":"\t\t
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Stein Aerts<\/span><\/span> est le directeur fondateur du VIB Center for AI and Computational Biology<\/span><\/span><\/a> \u00e0 Leuven<\/span><\/span>, en Belgique<\/span><\/span>. Son laboratoire<\/a> combine de mani\u00e8re originale le d\u00e9veloppement de logiciels et de nouvelles technologies, l\u2019utilisation de mod\u00e8les de drosophiles et de souris, ainsi que des approches de machine learning, pour comprendre comment les s\u00e9quences d\u2019ADN sont interpr\u00e9t\u00e9es par les facteurs de transcription et d\u2019autres prot\u00e9ines de la chromatine afin de fa\u00e7onner des types cellulaires sp\u00e9cifiques chez des organismes complexes, notamment dans les cerveaux des drosophiles, des oiseaux et des mammif\u00e8res.<\/p>

L\u2019\u00e9quipe de Stein Aerts<\/span><\/span> a apport\u00e9 des contributions majeures \u00e0 notre compr\u00e9hension de la mani\u00e8re dont le code g\u00e9nomique est interpr\u00e9t\u00e9 et dont il r\u00e9gule les \u00e9tats physiologiques et pathologiques.<\/p>

Parmi ses nombreuses d\u00e9couvertes fondamentales, Stein Aerts a jou\u00e9 un r\u00f4le cl\u00e9 dans le Fly Cell Atlas<\/span><\/span><\/a>, qui a permis de d\u00e9finir la majorit\u00e9 des types cellulaires chez la drosophile. Son \u00e9quipe a \u00e9galement mis en \u00e9vidence des similarit\u00e9s inattendues entre les cerveaux des mammif\u00e8res et des oiseaux<\/a>, et r\u00e9ussi \u00e0 g\u00e9n\u00e9rer des enhancers synth\u00e9tiques complets permettant une expression sp\u00e9cifique \u00e0 certains tissus<\/a>.<\/p>

Son laboratoire a aussi d\u00e9velopp\u00e9 SCENIC<\/span><\/span><\/a>, SCope<\/span><\/span><\/a> et plusieurs autres outils que beaucoup d\u2019entre vous ont probablement utilis\u00e9s pour analyser des donn\u00e9es d\u2019omiques en cellule unique.<\/p><\/div><\/div><\/div><\/div>

\u00a0<\/div>
\ud83d\udd67 <\/strong>Vendredi 22\/05\/2026 \u00e0 11h30 | Amphi 12<\/h6><\/div><\/div><\/section><\/div><\/div><\/div><\/div><\/div><\/div><\/section><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><\/div><\/div>
\ud83e\uddec Genome-to-function modeling<\/h6>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Rejoignez-nous pour un s\u00e9minaire de Stein Aerts intitul\u00e9 \u00ab Genome-to-function modeling \u00bb, le 22 mai 2026 en Amphi 12.<\/p>\n","protected":false},"author":27,"featured_media":23491,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[79],"tags":[16],"class_list":["post-23487","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news-fr","tag-headline-news"],"acf":[],"_links":{"self":[{"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/posts\/23487","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/users\/27"}],"replies":[{"embeddable":true,"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/comments?post=23487"}],"version-history":[{"count":7,"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/posts\/23487\/revisions"}],"predecessor-version":[{"id":23505,"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/posts\/23487\/revisions\/23505"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/media\/23491"}],"wp:attachment":[{"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/media?parent=23487"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/categories?post=23487"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/tags?post=23487"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}