{"id":9291,"date":"2022-02-05T00:00:45","date_gmt":"2022-02-04T23:00:45","guid":{"rendered":"https:\/\/staging.wp-ibdm.nicolasg.fr\/recherche\/chacun-son-destin-comment-les-cellules-acquierent-leur-identite\/"},"modified":"2023-03-10T06:52:39","modified_gmt":"2023-03-10T05:52:39","slug":"chacun-son-destin-comment-les-cellules-acquierent-leur-identite","status":"publish","type":"page","link":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/recherche\/chacun-son-destin-comment-les-cellules-acquierent-leur-identite\/","title":{"rendered":"Chacun son destin : comment les cellules acqui\u00e8rent leur identit\u00e9 ?"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"9291\" class=\"elementor elementor-9291 elementor-1643\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-860403e elementor-section-full_width elementor-section-height-min-height elementor-section-height-default elementor-section-items-middle\" data-id=\"860403e\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;background_motion_fx_motion_fx_scrolling&quot;:&quot;yes&quot;,&quot;background_motion_fx_translateY_effect&quot;:&quot;yes&quot;,&quot;background_motion_fx_translateY_speed&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:4,&quot;sizes&quot;:[]},&quot;background_motion_fx_translateY_affectedRange&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:{&quot;start&quot;:0,&quot;end&quot;:100}},&quot;background_motion_fx_devices&quot;:[&quot;desktop&quot;,&quot;tablet&quot;,&quot;mobile&quot;]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-b2943a6\" data-id=\"b2943a6\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-f4ef8ac elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"f4ef8ac\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-daa1eb1\" data-id=\"daa1eb1\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-1983a06 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1983a06\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-d727ae2\" data-id=\"d727ae2\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1d44fba elementor-widget elementor-widget-heading\" data-id=\"1d44fba\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Chacun son destin :<br>\ncomment les cellules acqui\u00e8rent leur identit\u00e9 ?<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-8477069\" data-id=\"8477069\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9f2c55c elementor-widget elementor-widget-text-editor\" data-id=\"9f2c55c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Notre corps contient de nombreux types de cellules diff\u00e9rentes, comme les cellules cardiaques, nerveuses, musculaires ou cutan\u00e9es, qui poss\u00e8dent des caract\u00e9ristiques tr\u00e8s sp\u00e9cifiques leur permettant de faire leur travail. Pourtant, toutes les cellules d&#8217;un organisme donn\u00e9 sont issues d&#8217;une cellule unique, l&#8217;oeuf f\u00e9cond\u00e9, et contiennent donc la m\u00eame information g\u00e9n\u00e9tique. Au fur et \u00e0 mesure que les cellules prolif\u00e8rent pendant le d\u00e9veloppement embryonnaire, elles acqui\u00e8rent progressivement leur identit\u00e9 unique, guid\u00e9es par l&#8217;expression d&#8217;ensembles particuliers de g\u00e8nes qui d\u00e9terminent les propri\u00e9t\u00e9s uniques de chaque type de cellule. \u00c0 l&#8217;IBDM, nous voulons comprendre les m\u00e9canismes qui contr\u00f4lent l\u2019acquisition de l&#8217;identit\u00e9 cellulaire au cours du d\u00e9veloppement, et comment la grande diversit\u00e9 des types de cellules dans les organismes multicellulaires d&#8217;aujourd&#8217;hui est apparue au cours de l&#8217;\u00e9volution. \u00c0 cette fin, nous nous concentrons sur le r\u00f4le des facteurs de transcription et des interrupteurs g\u00e9n\u00e9tiques qu&#8217;ils contr\u00f4lent, sur la mani\u00e8re dont les mol\u00e9cules d&#8217;ARN non-codant r\u00e9duisent les g\u00e8nes de mani\u00e8re post-transcriptionnelle, sur la mani\u00e8re dont les signaux biochimiques et m\u00e9caniques envoy\u00e9s par les cellules voisines sont per\u00e7us et int\u00e9gr\u00e9s pour instruire le destin cellulaire ou modifier l&#8217;\u00e9tat m\u00e9tabolique de l&#8217;organisme.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-298d02c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"298d02c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-f7873a0\" data-id=\"f7873a0\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8e23d03 elementor-widget elementor-widget-post-navigation\" data-id=\"8e23d03\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"post-navigation.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-post-navigation\" role=\"navigation\" aria-label=\"Post Navigation\">\n\t\t\t<div class=\"elementor-post-navigation__prev elementor-post-navigation__link\">\n\t\t\t\t<a href=\"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/recherche\/les-briques-du-vivant-de-la-molecule-a-larchitecture-cellulaire\/\" rel=\"prev\"><span class=\"post-navigation__arrow-wrapper post-navigation__arrow-prev\"><i aria-hidden=\"true\" class=\"fas fa-angle-left\"><\/i><span class=\"elementor-screen-only\">Prev<\/span><\/span><span class=\"elementor-post-navigation__link__prev\"><span class=\"post-navigation__prev--label\">Th\u00e8me pr\u00e9c\u00e9dent<\/span><span class=\"post-navigation__prev--title\">Les briques du vivant : de la mol\u00e9cule \u00e0 l\u2019architecture cellulaire<\/span><\/span><\/a>\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"elementor-post-navigation__next elementor-post-navigation__link\">\n\t\t\t\t<a href=\"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/recherche\/origamis-vivants-comment-les-formes-et-les-fonctions-des-organes-emergent-et-evoluent\/\" rel=\"next\"><span class=\"elementor-post-navigation__link__next\"><span class=\"post-navigation__next--label\">Th\u00e8me suivant<\/span><span class=\"post-navigation__next--title\">Origamis vivants : Comment les formes et les fonctions des organes \u00e9mergent et \u00e9voluent ?<\/span><\/span><span class=\"post-navigation__arrow-wrapper post-navigation__arrow-next\"><i aria-hidden=\"true\" class=\"fas fa-angle-right\"><\/i><span class=\"elementor-screen-only\">Next<\/span><\/span><\/a>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1ba4e6c elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"1ba4e6c\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-70f7332\" data-id=\"70f7332\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-6adb4a0 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6adb4a0\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-f200c5d\" data-id=\"f200c5d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-951be01 elementor-widget__width-auto elementor-widget elementor-widget-heading\" data-id=\"951be01\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Equipes de recherche<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-1d2ea31 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1d2ea31\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-b3803b5\" data-id=\"b3803b5\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Chacun son destin : comment les cellules acqui\u00e8rent leur identit\u00e9 ? Notre corps contient de nombreux types de cellules diff\u00e9rentes, comme les cellules cardiaques, nerveuses, musculaires ou cutan\u00e9es, qui poss\u00e8dent des caract\u00e9ristiques tr\u00e8s sp\u00e9cifiques leur permettant de faire leur travail. Pourtant, toutes les cellules d&#8217;un organisme donn\u00e9 sont issues d&#8217;une cellule unique, l&#8217;oeuf f\u00e9cond\u00e9, et [&hellip;]<\/p>\n","protected":false},"author":26,"featured_media":2328,"parent":9190,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"elementor_theme","meta":{"_acf_changed":false,"footnotes":""},"category-theme":[121],"class_list":["post-9291","page","type-page","status-publish","has-post-thumbnail","hentry","theme-the-road-to-self","category-theme-research-theme"],"acf":[],"_links":{"self":[{"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/pages\/9291","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/users\/26"}],"replies":[{"embeddable":true,"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/comments?post=9291"}],"version-history":[{"count":9,"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/pages\/9291\/revisions"}],"predecessor-version":[{"id":15592,"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/pages\/9291\/revisions\/15592"}],"up":[{"embeddable":true,"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/pages\/9190"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/media\/2328"}],"wp:attachment":[{"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/media?parent=9291"}],"wp:term":[{"taxonomy":"category-theme","embeddable":true,"href":"https:\/\/staging.wp-ibdm.nicolasg.fr\/fr\/wp-json\/wp\/v2\/category-theme?post=9291"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}