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Nervous But Sympathetic !
In this study, the Mann team showed that pancreatic cancer development promotes the sprouting and growth of sympathetic axons.
INSTITUTE OF DEVELOPMENTAL BIOLOGY
In this study, the Mann team showed that pancreatic cancer development promotes the sprouting and growth of sympathetic axons.
The Helmbacher team identified the Fat1 Cadherin as a novel regulator of retinal vascular integrity, and investigated the underlying mechanisms.
Our work demonstrates that by activating the NF-kB pathway, cell wall peptidoglycan produced by these same bacteria, counteracts SREBP activation in adipocytes in a cell-autonomous manner.
Our results allow us to propose a simple and efficient model of how life could generate new functions through the use of new actin isoforms.
Data published in Hum Mol Genet. confirm that Tshz3 heterozygous mice constitute a model that replicates many of the clinical problems reported in patients with TSHZ3 heterozygous conditions.
The selected candidates will receive support to establish a group in a fully renovated building, have access to cutting-edge scientific core facilities, and will be assisted in obtaining a tenured position, and in securing extramural funding.
Our findings provide mechanistic insight into the mechanism by which TAFA4 reverses injury-induced mechanical hypersensitivity, by restoring normal spinal neuron activity, and highlight the considerable potential of TAFA4 as a treatment for injury-induced mechanical pain.
Lydia Kerkerian-Le Goff, Research Director at the CNRS and head of the Cellular Interactions, Neurodegeneration and Neuroplasticity team at the Marseille Institute of Developmental Biology (IBDM)
Through an international collaboration, using breast cancer as a biological paradigm, Flavio Maina Team publishes a work in the Theranostics journal exemplifying how specificity in targeting cell cycle regulators is essential for combinatorial cancer therapies.
Ardem Patapoutian shares the honours of his Nobel Prize with his former post-docs and students including Aziz Moqrich, Chronic pain : Molecular and cellular mechanisms